Have ridden bikes with plugged tyres in the past with no problem whatsoever. Had several such tyres when I was riding a VFR800 which is a heavy bike and a sporty ride. Tyres lasted to the end of their natural life - no problem with leaks. It's more of a mindset thing. Just ride to the conditions and try not to think about the plug. A vulcanised plug correctly installed will not cause any issues. Once you've had a couple of rides you will forget it is there.